Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1256468 | 0.97 | SIGMAR1 (0.43) | SIGMAR1DRD2ADRA1ADRD3ACHE | |
| SCHEMBL1256469 | 0.86 | SIGMAR1 (0.41) | SIGMAR1DRD2ADRA1ADRD3ACHE | |
| SCHEMBL1257965 | 0.85 | DRD2 (0.43) | SIGMAR1DRD2ADRA1ADRD3ACHE | |
| Hydrochloric Acid SCHEMBL1256889 | 0.81 | DRD2 (0.44) | SIGMAR1DRD2ADRA1ADRD3ACHE | |
| SCHEMBL1256817 | 0.79 | RET (0.51) | KDR | |
| SCHEMBL1256232 | 0.77 | CD274 (0.51) | DRD2ADRA1ADRD3ACHEKDR | |
| SCHEMBL14673876 | 0.77 | RET (0.49) | KDR | |
| SCHEMBL25379528 | 0.74 | HRH3 (0.45) | SIGMAR1DRD2HRH3 | |
| SCHEMBL1255230 | 0.74 | SIGMAR1 (0.48) | SIGMAR1FYNHRH3LMNATSHR | |
| SCHEMBL1255322 | 0.73 | ABCC4 (0.49) | WNT3AABCC4LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467137-A1 | BIARYL COMPOUNDS AND METHODS OF USE THEREOF | Ambit Biosciences Corporation (US) | 2012-06-27 | — | — | EP | disclosed |