Quercetin

Quercetin

SCHEMBL9958875

O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12.[PbH2]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.97
KMT2A Q03164 11/20 0.97
CYP1A2 P05177 8/20 0.97
CYP3A4 P08684 8/20 0.97
KDM4E B2RXH2 8/20 0.97
HSD17B10 Q99714 8/20 0.97
MAPT P10636 8/20 0.97
CYP2C9 P11712 7/20 0.97
RECQL P46063 7/20 0.97
CYP1A1 P04798 7/20 0.97
CYP1B1 Q16678 7/20 0.97
XDH P47989 7/20 0.97
FTO Q9C0B1 7/20 0.97
ALOX15 P16050 6/20 0.97
ABCB1 P08183 6/20 0.97
APP P05067 6/20 0.97
POLH Q9Y253 6/20 0.97
POLB P06746 5/20 0.97
TP53 P04637 5/20 0.97
IPMK Q8NFU5 5/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quercetin SCHEMBL29353785 0.99 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL118425 0.99 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL31507620 0.99 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL19723 0.99 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL17629824 0.99 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL29351036 0.99 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL29723041 0.99 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL3786991 0.97 MEN1 (0.97) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL6756842 0.97 MEN1 (0.97) MEN1KMT2ACYP1A2CYP3A4KDM4E
Quercetin SCHEMBL22103 0.97 MEN1 (1.00) MEN1KMT2ACYP1A2CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12195437-B2 Lipophenolic flavonoid derivatives useful to reduce carbonyl and oxidative stresses (COS) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2025-01-14 US disclosed
CN-114196351-B Aging-resistant lithium battery sealant and preparation method thereof 江苏强劲新能源科技有限公司 2024-01-12 CN disclosed
EP-3820857-A1 LIPOPHENOLIC FLAVONOID DERIVATIVES USEFUL TO REDUCE CARBONYL AND OXIDATIVE STRESSES (COS) Centre National de la Recherche Scientifique (CNRS) (FR) 2021-05-19 EP disclosed
US-20210139447-A1 Lipophenolic Flavonoid Derivatives Useful To Reduce Carbonyl And Oxidative Stresses (COS) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2021-05-13 US disclosed
WO-2020012003-A1 LIPOPHENOLIC FLAVONOID DERIVATIVES USEFUL TO REDUCE CARBONYL AND OXIDATIVE STRESSES (COS) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2020-01-16 WO disclosed
CN-107334761-A Medical composition and its use 中国科学院化学研究所 2017-11-10 CN disclosed
EP-2468741-A1 Novel quercetin derivatives, their preparation, pharmaceutical compositions containing them and their use Bel/Novamann International s.r.o. (SK) 2012-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12195437-B2 Lipophenolic flavonoid derivatives useful to reduce carbonyl and oxidative stresses (COS) LPO, NQO1, CAT MEN1 3920/4885KMT2A 4226/4885CYP1A2 133/4885
US-20210139447-A1 Lipophenolic Flavonoid Derivatives Useful To Reduce Carbonyl And Oxidative Stresses (COS) LPO, NQO1, CAT MEN1 3920/4885KMT2A 4226/4885CYP1A2 133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.