Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857133 | 0.82 | METAP1 (0.44) | METAP2METAP1 | |
| SCHEMBL9959654 | 0.81 | STAT3 (0.42) | STAT3CA1CA2CA9CA4 | |
| SCHEMBL1728666 | 0.80 | STAT3 (0.46) | STAT3 | |
| SCHEMBL1728670 | 0.77 | STAT3 (0.46) | STAT3CA1CA2CA9CA12 | |
| SCHEMBL15258967 | 0.77 | SOS1 (0.37) | STAT3CA1CA2CA9CA4 | |
| SCHEMBL1093963 | 0.76 | IDO1 (0.44) | STAT3CA1CA2CA9CA4 | |
| SCHEMBL16947690 | 0.72 | — | — | |
| SCHEMBL23235485 | 0.71 | MDM2 (0.38) | STAT3CA1CA2CA9 | |
| Formic Acid SCHEMBL19616984 | 0.71 | STAT3 (0.41) | STAT3CA1CA2CA9CA4 | |
| SCHEMBL22606378 | 0.70 | STAT3 (0.69) | STAT3CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |