⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692394 | 0.79 | — | — | |
| SCHEMBL1337277 | 0.79 | — | — | |
| SCHEMBL279417 | 0.77 | — | — | |
| SCHEMBL13505930 | 0.77 | ALDH1A1 (0.51) | — | |
| SCHEMBL27734758 | 0.74 | — | — | |
| SCHEMBL13689292 | 0.74 | HMBS (0.41) | — | |
| SCHEMBL30395996 | 0.74 | SMYD3 (0.47) | — | |
| SCHEMBL18415314 | 0.74 | CREBBP (0.63) | — | |
| SCHEMBL14413703 | 0.73 | — | — | |
| SCHEMBL4550730 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112839936-B | Novel N- (isopropyl-triazolyl) pyridinyl) -heteroaryl-carboxamide derivatives and their use | 怡诺安有限公司 | 2025-05-16 | — | — | CN | disclosed |
| US-12077523-B2 | N-(isopropyl-triazolyl)pyridinyl)-heteroaryl-carboxamide derivatives and use thereof | HK INNO.N CORPORATION (KR) | 2024-09-03 | — | — | US | disclosed |
| EP-3867243-B1 | NOVEL N-(ISOPROPYL-TRIAZOLYL)PYRIDINYL)-HETEROARYL-CARBOXAMIDE DERIVATIVES AND USE THEREOF | HK INNO N CORP (KR) | 2024-06-05 | — | — | EP | disclosed |
| US-20220033378-A1 | NOVEL N-(ISOPROPYL-TRIAZOLYL)PYRIDINYL)-HETEROARYL-CARBOXAMIDE DERIVATIVES AND USE THEREOF | HK INNO.N CORPORATION (KR) | 2022-02-03 | — | — | US | disclosed |
| US-20220033378-A1 | NOVEL N-(ISOPROPYL-TRIAZOLYL)PYRIDINYL)-HETEROARYL-CARBOXAMIDE DERIVATIVES AND USE THEREOF | HK INNO.N CORPORATION (KR) | 2022-02-03 | — | — | US | disclosed |
| CN-112839936-A | Novel N- (isopropyl-triazolyl) pyridyl) -heteroaryl-carboxamide derivatives and uses thereof | 怡诺安有限公司 | 2021-05-25 | — | — | CN | disclosed |
| EP-2655323-B1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LTD (IE) | 2017-12-20 | — | — | EP | disclosed |
| US-20170217910-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LIMITED (IE) | 2017-08-03 | — | — | US | disclosed |
| US-9708286-B2 | Ingenol-3-acylates III and ingenol-3-carbamates | LEO LABORATORIES LIMITED (IE) | 2017-07-18 | — | — | US | disclosed |
| US-20150291551-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LIMITED (IE) | 2015-10-15 | — | — | US | disclosed |
| US-9102687-B2 | Ingenol-3-acylates III and ingenol-3-carbamates | LEO LABORATORIES LIMITED (IE) | 2015-08-11 | — | — | US | disclosed |
| US-20140303150-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LIMITED (IE) | 2014-10-09 | — | — | US | disclosed |
| EP-2655323-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LIMITED (IE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012083953-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO PHARMA A/S (DK) | 2012-06-28 | — | — | WO | disclosed |