Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 13/20 | 0.55 |
| ▸ | LPAR5 | Q9H1C0 | 9/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957519 | 0.82 | UTS2R (0.39) | C5AR1RCE1 | |
| SCHEMBL9957640 | 0.81 | C5AR1 (0.37) | LPAR1LPAR5LPAR2C5AR1RCE1 | |
| SCHEMBL3583296 | 0.77 | LPAR1 (0.52) | LPAR1LPAR5LPAR2C5AR1STAT3 | |
| SCHEMBL3584106 | 0.74 | LPAR1 (0.59) | LPAR1LPAR5LPAR2C5AR1STAT3 | |
| SCHEMBL16507529 | 0.71 | LPAR1 (1.00) | LPAR1LPAR5 | |
| SCHEMBL9081131 | 0.70 | LPAR1 (0.64) | LPAR1LPAR5STAT3 | |
| SCHEMBL9082102 | 0.70 | LPAR1 (0.64) | LPAR1LPAR5STAT3 | |
| SCHEMBL17923569 | 0.70 | LPAR1 (0.78) | LPAR1LPAR5LPAR2RCE1 | |
| SCHEMBL16506924 | 0.70 | LPAR1 (0.81) | LPAR1LPAR5LPAR2RCE1 | |
| SCHEMBL5739117 | 0.69 | LPAR1 (0.59) | LPAR1LPAR5RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |