Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957519 | 0.92 | UTS2R (0.39) | C5AR1CRHR1RCE1CA12CA1 | |
| SCHEMBL9960423 | 0.81 | LPAR1 (0.55) | C5AR1RCE1LPAR1LPAR5LPAR2 | |
| SCHEMBL12521064 | 0.78 | C5AR1 (0.45) | C5AR1RCE1MLYCDCA12CA1 | |
| SCHEMBL3577052 | 0.77 | C5AR1 (0.37) | C5AR1RCE1MAPTMLYCDCA12 | |
| SCHEMBL27730382 | 0.75 | C5AR1 (0.39) | C5AR1RCE1MAPTMLYCDMCL1 | |
| SCHEMBL12521151 | 0.75 | LPAR1 (0.40) | C5AR1RCE1CA12CA1CA2 | |
| SCHEMBL3577159 | 0.74 | C5AR1 (0.42) | C5AR1CA12CA1CA2CA4 | |
| SCHEMBL27731179 | 0.74 | C5AR1 (0.51) | C5AR1RCE1MAPTMLYCDLPAR1 | |
| SCHEMBL12521253 | 0.74 | UTS2R (0.40) | C5AR1RCE1MAPTLPAR1LPAR5 | |
| SCHEMBL9957726 | 0.73 | MLYCD (0.34) | CRHR1RCE1MAPTMLYCDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |