Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 12/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 9/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3589192 | 0.86 | PPARA (0.39) | LPAR1LPAR5C5AR1RCE1 | |
| SCHEMBL3584106 | 0.84 | LPAR1 (0.59) | LPAR1LPAR5LTA4HEPHX2C5AR1 | |
| SCHEMBL3580876 | 0.83 | LPAR1 (0.36) | LPAR1LPAR5EPHX2C5AR1RCE1 | |
| SCHEMBL3578978 | 0.83 | CNR1 (0.43) | LPAR1LPAR5EPHX2C5AR1RCE1 | |
| SCHEMBL3583039 | 0.82 | CNR1 (0.43) | C5AR1RCE1 | |
| SCHEMBL3577052 | 0.81 | C5AR1 (0.37) | LPAR1LPAR5C5AR1RCE1 | |
| SCHEMBL3576227 | 0.80 | ALDH1A1 (0.37) | LPAR1LPAR5C5AR1RCE1 | |
| SCHEMBL9960423 | 0.77 | LPAR1 (0.55) | LPAR1LPAR5LTA4HEPHX2C5AR1 | |
| SCHEMBL3579938 | 0.76 | MAPT (0.42) | LPAR1LPAR5EPHX2RCE1 | |
| SCHEMBL3581545 | 0.75 | CNR1 (0.40) | LPAR1LPAR5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |