Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 10/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 4/20 | 0.42 |
| ▸ | SRC | P12931 | 4/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713695 | 0.76 | AXL (0.59) | IKBKETBK1KDRCHEK2 | |
| SCHEMBL741344 | 0.73 | PIK3CA (0.61) | PIK3CAIKBKETBK1CHEK2PIK3CG | |
| SCHEMBL13188536 | 0.72 | IKBKE (0.57) | IKBKETBK1CHEK2 | |
| SCHEMBL29041964 | 0.72 | IRAK4 (0.48) | — | |
| SCHEMBL30508232 | 0.72 | IRAK4 (0.48) | — | |
| Hydrochloric Acid SCHEMBL29786530 | 0.72 | PIK3CG (0.49) | PIK3CAIKBKETBK1ALOX5APCHEK2 | |
| SCHEMBL9954448 | 0.72 | PI4KA (0.63) | IKBKETBK1PIK3CG | |
| SCHEMBL25750391 | 0.72 | BRAF (0.63) | PIK3CALCKKDRJAK3MAPK14 | |
| SCHEMBL5492585 | 0.72 | LCK (0.59) | LCKKDRJAK3MAPK14TNKS | |
| SCHEMBL28080193 | 0.71 | LCK (0.54) | LCKKDRJAK3MAPK14KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |