Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034267 | 0.82 | KIF11 (0.57) | KIF11HRH3LMNATSHRMAPT | |
| SCHEMBL9951484 | 0.78 | KIF11 (0.41) | KIF11HRH3LMNATSHRMAPT | |
| SCHEMBL9952379 | 0.77 | KIF11 (0.40) | KIF11HRH3MAPTHTTNPC1 | |
| SCHEMBL15784743 | 0.76 | AKT1 (0.59) | KIF11HRH3LMNATSHRMAPT | |
| SCHEMBL15784754 | 0.76 | AKT1 (0.59) | KIF11HRH3LMNATSHRMAPT | |
| SCHEMBL820736 | 0.75 | KIF11 (0.71) | KIF11LMNATSHRMAPTHPGD | |
| SCHEMBL65312 | 0.75 | KIF11 (0.71) | KIF11LMNATSHRMAPTHPGD | |
| SCHEMBL12169275 | 0.73 | TSHR (0.48) | KIF11LMNATSHRMAPTHPGD | |
| SCHEMBL20137330 | 0.73 | KIF11 (0.68) | KIF11LMNATSHRMAPTHPGD | |
| Lithium SCHEMBL29576172 | 0.73 | KIF11 (0.68) | KIF11LMNATSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087630-A1 | PYRIDINE AND PYRIMIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | claimed |
| WO-2012087630-A1 | PYRIDINE AND PYRIMIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |