Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973193 | 0.89 | PTPN1 (0.45) | CASP3PTPN1 | |
| SCHEMBL29609769 | 0.82 | CASP3 (0.55) | CASP3 | |
| SCHEMBL16770356 | 0.81 | CASP3 (0.46) | CASP3PTPN1 | |
| SCHEMBL19015950 | 0.80 | CASP3 (0.50) | CASP3ALDH1A1 | |
| SCHEMBL7882598 | 0.80 | CASP3 (0.50) | CASP3ALDH1A1 | |
| SCHEMBL7890585 | 0.79 | CASP3 (0.46) | CASP3 | |
| SCHEMBL12513415 | 0.78 | PTPN1 (0.43) | CASP3PTPN1ALDH1A1 | |
| SCHEMBL29767979 | 0.78 | CASP3 (0.52) | CASP3PTPN1 | |
| SCHEMBL20099715 | 0.78 | PTPN1 (0.45) | CASP3PTPN1ALDH1A1 | |
| SCHEMBL26328832 | 0.78 | PTPN1 (0.45) | CASP3PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157394-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES, INC. (CA) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157394-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | CASP1, VIP, CASP5 | CASP3 6/4885PTPN1 3562/4885ALDH1A1 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.