Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30446328 | 0.88 | MAPT (0.73) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL400288 | 0.88 | MAPT (0.73) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL16281785 | 0.86 | MAPT (0.76) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL20746326 | 0.81 | KDM4E (0.50) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL17041929 | 0.80 | PTGS1 (0.41) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL105520 | 0.79 | KDM4E (0.71) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL19366780 | 0.78 | MTNR1A (0.65) | ALDH1A1LMNAMAPK1TSHR | |
| Protocatechualdehyde SCHEMBL23610641 | 0.78 | MAPT (0.59) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL22212822 | 0.77 | MAPT (0.49) | MAPTALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL11899577 | 0.77 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202956-B2 | Copolymers having zwitterionic moieties and dihydroxyphenyl moieties and medical devices coated with the copolymers | ABBOTT LABORATORIES (US) | 2012-06-19 | — | — | US | disclosed |
| US-20110160382-A1 | COPOLYMERS HAVING ZWITTERIONIC MOIETIES AND DIHDROXYPHENYL MOIETIES AND MEDICAL DEVICES COATED WITH THE COPOLYMERS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | US | disclosed |