⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13274743 | 0.78 | ADORA2A (0.38) | — | |
| SCHEMBL18250743 | 0.75 | L3MBTL1 (0.36) | — | |
| SCHEMBL8128909 | 0.74 | CYP3A4 (0.33) | — | |
| SCHEMBL23867483 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL18250740 | 0.74 | CYP3A4 (0.35) | — | |
| SCHEMBL22409022 | 0.73 | — | — | |
| SCHEMBL15201966 | 0.73 | — | — | |
| SCHEMBL23154363 | 0.73 | — | — | |
| SCHEMBL15202154 | 0.73 | — | — | |
| SCHEMBL12789238 | 0.73 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742168-B2 | Process for the production of acetic acid | LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) | 2014-06-03 | — | — | US | claimed |
| US-8637699-B2 | Process for the manufacture of acetic acid | LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) | 2014-01-28 | — | — | US | claimed |
| US-20120310009-A1 | Process for the Production of Acetic Acid | LYONDELL CHEMICAL COMPANY (US) | 2012-12-06 | — | — | US | claimed |
| US-20120264971-A1 | PROCESS FOR THE MANUFACTURE OF ACETIC ACID | LYONDELLBASELL ACETYLS, LLC | 2012-10-18 | — | — | US | claimed |
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| EP-3790886-B1 | KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER | AMGEN INC (US) | 2024-06-26 | — | — | EP | disclosed |
| US-12018011-B2 | Macrocyclic compounds and compositions, and methods of preparing and using the same | KURA ONCOLOGY, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-12018011-B2 | Macrocyclic compounds and compositions, and methods of preparing and using the same | KURA ONCOLOGY, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20230382891-A1 | GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE (QPCTL) PROTEIN INHIBITORS AND USES THEREOF | BLACKSMITH MEDICINES, INC. | 2023-11-30 | — | — | US | disclosed |
| EP-4269399-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | disclosed |
| US-20230322711-A1 | MACROCYCLIC COMPOUNDS AND COMPOSITIONS, AND METHODS OF PREPARING AND USING THE SAME | WUXI APPTEC (HONG KONG) LIMITED (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20120157432-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME, CORP. (US) | 2012-06-21 | — | — | US | disclosed |
| CN-101273423-B | Electrolyte solution for electrochemical device and electrochemical device using same | SANYO CHEMICAL IND LTD | 2011-01-26 | — | — | CN | disclosed |
| US-20090270434-A1 | AZACYCLOALKANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | LEBLANC YVES | 2009-10-29 | — | — | US | disclosed |
| US-7582633-B2 | Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase | MERCK FROSST CANADA L.L.C. (CA) | 2009-09-01 | — | — | US | disclosed |
| CN-101273423-A | Electrolyte solution for electrochemical device and electrochemical device using same | SANYO CHEMICAL IND LTD (JP) | 2008-09-24 | — | — | CN | disclosed |
| US-20080182838-A1 | Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase | MERCK CANADA INC. (CA) | 2008-07-31 | — | — | US | disclosed |
| US-7342016-B2 | Farnesyl protein transferase inhibitors as antitumor agents | SCHERING CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-4108857-A | CNS DEPRESSANTS, ANALGESICS, PSYCHOMOTOR ACTION | STERLING DRUG INC. (US) | 1978-08-22 | — | — | US | disclosed |