Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996382 | 1.00 | TNFRSF1A (0.58) | TNFRSF1AALDH1A1LMNAMAPTABCG2 | |
| SCHEMBL998110 | 0.92 | ABCG2 (0.65) | TNFRSF1AALDH1A1LMNAMAPTABCG2 | |
| SCHEMBL998114 | 0.92 | ABCG2 (0.65) | TNFRSF1AALDH1A1LMNAMAPTABCG2 | |
| SCHEMBL996599 | 0.85 | TUBB4A (0.60) | TNFRSF1AALDH1A1LMNAMAPTABCG2 | |
| SCHEMBL996596 | 0.85 | TUBB4A (0.60) | TNFRSF1AALDH1A1LMNAMAPTABCG2 | |
| SCHEMBL998057 | 0.84 | TUBB4A (0.70) | TNFRSF1ALMNAMAPTABCG2APP | |
| SCHEMBL998056 | 0.84 | TUBB4A (0.70) | TNFRSF1ALMNAMAPTABCG2APP | |
| SCHEMBL30307328 | 0.82 | RAB9A (0.71) | TNFRSF1AALDH1A1LMNAMAPTABCG2 | |
| SCHEMBL996172 | 0.82 | TUBB4A (0.74) | TNFRSF1AALDH1A1LMNAMAPTABCG2 | |
| SCHEMBL996173 | 0.82 | TUBB4A (0.74) | TNFRSF1AALDH1A1LMNAMAPTABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |