⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459678 | 1.00 | — | — | |
| SCHEMBL10459644 | 0.89 | — | — | |
| SCHEMBL10459829 | 0.81 | TDP1 (0.31) | — | |
| SCHEMBL18490356 | 0.78 | STING1 (0.32) | — | |
| SCHEMBL10457924 | 0.78 | — | — | |
| SCHEMBL22758781 | 0.76 | ATG7 (0.37) | — | |
| SCHEMBL22758763 | 0.76 | ATG7 (0.37) | — | |
| SCHEMBL10459778 | 0.75 | PDE4A (0.42) | — | |
| SCHEMBL19880314 | 0.75 | PDE4A (0.42) | — | |
| SCHEMBL12899479 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186826-A1 | PROTECTED MONOMER AND METHOD OF FINAL DEPROTECTION FOR RNA SYNTHESIS | AGILENT TECHNOLOGIES, INC. | 2018-07-05 | — | — | US | disclosed |
| US-8202983-B2 | Thiocarbon-protecting groups for RNA synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20090209479-A1 | THIOCARBON-PROTECTING GROUPS FOR RNA SYNTHESIS | AGILENT TECHNOLOGIES, INC. | 2009-08-20 | — | — | US | disclosed |