Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965242 | 0.83 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL18231628 | 0.81 | — | — | |
| SCHEMBL14527794 | 0.80 | KDM4E (0.31) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL19322614 | 0.77 | — | — | |
| SCHEMBL23431353 | 0.77 | — | — | |
| SCHEMBL19257180 | 0.74 | KDM4E (0.41) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL783198 | 0.72 | USP2 (0.56) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL22892502 | 0.71 | NR3C2 (0.33) | — | |
| SCHEMBL881573 | 0.70 | ALDH1A1 (0.39) | KDM4EALDH1A1LMNA | |
| SCHEMBL3694219 | 0.70 | USP2 (0.52) | USP2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3406614-B1 | OPIOID RECEPTOR ANTAGONIST CONJUGATE AND USE THEREOF | SHANGHAI HANMAI BIO PHARMA CO LTD (CN) | 2022-12-28 | — | — | EP | disclosed |
| US-20150174264-A1 | Oligomer-Antihistamine Conjugates | NEKTAR THERAPEUTICS (US) | 2015-06-25 | — | — | US | disclosed |
| US-8895068-B2 | Nanoparticle composition and associated methods thereof | GENERAL ELECTRIC COMPANY (US) | 2014-11-25 | — | — | US | disclosed |
| US-8889103-B2 | Diagnostic agent composition and associated methods thereof | GENERAL ELECTRIC COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| US-8269021-B2 | Aromatic imide-based dispersant for carbon nanotubes and carbon nanotube composition comprising the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-09-18 | — | — | US | disclosed |
| US-20120156141-A1 | NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF | GENERAL ELECTRIC COMPANY (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2012080290-A1 | NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF | GENERAL ELECTRIC COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20110227002-A1 | AROMATIC IMIDE-BASED DISPERSANT FOR CARBON NANOTUBES AND CARBON NANOTUBE COMPOSITION COMPRISING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-09-22 | — | — | US | disclosed |
| US-20100184989-A1 | De Novo Synthesis of Conjugates | NEKTAR THERAPEUTICS (US) | 2010-07-22 | — | — | US | disclosed |
| WO-2008112261-A1 | OLIGOMER-ANTICHOLINERGIC AGENT CONJUGATES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174264-A1 | Oligomer-Antihistamine Conjugates | HRH4, HRH1, HRH3 | USP2 572/4885TSHR 3564/4885KDM4E 3217/4885 |
| US-20100184989-A1 | De Novo Synthesis of Conjugates | ABCG2, UGT1A8, SLC7A5 | USP2 2222/4885TSHR 3018/4885KDM4E 4261/4885 |
| US-20110227002-A1 | AROMATIC IMIDE-BASED DISPERSANT FOR CARBON NANOTUBES AND CARBON NANOTUBE COMPOSITION COMPRISING THE SAME | EWSR1, NES, CENPE | USP2 1915/4885TSHR 4383/4885KDM4E 1526/4885 |
| US-20120156141-A1 | NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF | PHOSPHO1, PIK3CA, PTEN | USP2 2226/4885TSHR 3625/4885KDM4E 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.