Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319884 | 0.74 | CYP2D6 (0.64) | MEN1CYP2D6KMT2AHRH1LMNA | |
| Hydrochloric Acid SCHEMBL7321768 | 0.73 | CYP2D6 (0.62) | MEN1CYP2D6KMT2AHRH1LMNA | |
| SCHEMBL17689821 | 0.70 | CHRM2 (0.37) | MEN1CYP2D6KMT2AHRH1LMNA | |
| Azacyclonol SCHEMBL241817 | 0.70 | HRH1 (1.00) | MEN1CYP2D6KMT2AHRH1LMNA | |
| SCHEMBL360482 | 0.69 | CHRM2 (0.40) | CYP2D6HRH1CHRM2CHRM1CHRM3 | |
| SCHEMBL14018065 | 0.69 | KEAP1 (0.50) | HRH1CHRM2CHRM1CHRM3CYP1A2 | |
| Azacyclonol SCHEMBL1890138 | 0.69 | HRH1 (0.96) | MEN1CYP2D6KMT2AHRH1LMNA | |
| Azacyclonol SCHEMBL6135637 | 0.69 | HRH1 (0.96) | MEN1CYP2D6KMT2AHRH1LMNA | |
| SCHEMBL3951181 | 0.69 | CYP2D6 (0.70) | MEN1CYP2D6KMT2AHRH1LMNA | |
| SCHEMBL13145313 | 0.69 | CHRM2 (0.35) | CYP2D6HRH1LMNASCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667971-B1 | FEXOFENADINE POLYMORPHS AND PROCESSES OF PREPARING THE SAME | CIPLA LTD (IN) | 2012-06-20 | — | — | EP | disclosed |