SCHEMBL9965282

SCHEMBL9965282

Bc1c2ccccc2c(-c2c(C)cc(-c3cccc4ccccc34)cc2C)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.41
CA1 P00915 7/20 0.41
CA2 P00918 7/20 0.41
CA9 Q16790 7/20 0.41
ALDH1A1 P00352 3/20 0.40
CYP2A6 P11509 1/20 0.40
ENPP3 O14638 1/20 0.39
ENPP1 P22413 1/20 0.39
TLR8 Q9NR97 1/20 0.39
DHFR P00374 1/20 0.38
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
CYP1A2 P05177 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CHRNA1 P02708 1/20 0.36
CHRNG P07510 1/20 0.36
CHRNB1 P11230 1/20 0.36
CHRNB2 P17787 1/20 0.36
SLC6A2 P23975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15258011 0.84 CA12 (0.41) CA12CA1CA2CA9ALDH1A1
SCHEMBL9965252 0.84 TLR8 (0.49) CA12CA1CA2CA9ALDH1A1
SCHEMBL9965281 0.82 MAPT (0.44) CA12CA1CA2CA9ALDH1A1
SCHEMBL12839855 0.79 MCL1 (0.42) CA12CA1CA2CA9ALDH1A1
SCHEMBL13192354 0.78 CA12 (0.47) CA12CA1CA2CA9ENPP3
SCHEMBL28167268 0.78 ALDH1A1 (0.50) CA12CA1CA2CA9ALDH1A1
SCHEMBL13262306 0.77 DHFR (0.43) CA12CA1CA2CA9ALDH1A1
SCHEMBL18568364 0.76 CYP1A2 (0.47) ALDH1A1CYP2A6CYP1A2HPGD
SCHEMBL22517355 0.75 CA12 (0.49) CA12CA1CA2CA9ALDH1A1
SCHEMBL30719629 0.75 PTGS1 (0.53) CA12CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012083300-A1 ANTHRACENE DERIVATIVE COMPOUNDS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-21 WO disclosed