SCHEMBL9965294

SCHEMBL9965294

Cc1[nH]c(N)nc(=O)c1CCO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.46
CHEK1 O14757 1/20 0.43
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C19 P33261 1/20 0.35
GAA P10253 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
BACE1 P56817 1/20 0.34
MAPT P10636 1/20 0.34
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
TYK2 P29597 1/20 0.33
JAK3 P52333 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28459899 0.90 HSD17B10 (0.44) HSD17B10CHEK1KDM4EALDH1A1HTT
SCHEMBL11988258 0.81 HSD17B10 (0.54) HSD17B10KDM4EALDH1A1TSHRNPSR1
SCHEMBL28460640 0.81 HSD17B10 (0.42) HSD17B10KDM4EALDH1A1HTTNPSR1
SCHEMBL22372499 0.79 KMT2A (0.47) HSD17B10ALDH1A1HTTNPSR1GAA
SCHEMBL512553 0.79 NPSR1 (0.58) CHEK1KDM4EALDH1A1NPSR1MAPK1
SCHEMBL12192590 0.78 PKM (0.32) HSD17B10CHEK1ALDH1A1NPSR1MAPK1
SCHEMBL11988254 0.77 HSD17B10 (0.45) HSD17B10KDM4EALDH1A1HTTNPSR1
SCHEMBL22372496 0.77 HSD17B10 (0.46) HSD17B10ALDH1A1MAPK1CYP1A2CYP3A4
SCHEMBL9879042 0.76 HTT (0.40) CHEK1KDM4EALDH1A1TSHRHTT
SCHEMBL12193369 0.70 JAK2 (0.41) JAK2JAK1TYK2JAK3PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240171-A Polyurethane impact-resistant material containing quadruple hydrogen bonds and preparation method and application thereof 北京理工大学 2024-06-25 CN claimed
CN-111848907-A Supermolecule polyurethane impact-resistant material containing multiple hydrogen bonds and preparation method thereof 上海交通大学 2020-10-30 CN claimed
CN-119569984-A Biological plastic reinforced polyurethane foam and preparation method thereof 深圳安迪上科新材料科技有限公司 2025-03-07 CN disclosed
CN-118240171-A Polyurethane impact-resistant material containing quadruple hydrogen bonds and preparation method and application thereof 北京理工大学 2024-06-25 CN disclosed
CN-117417503-A Preparation and application of photo-curing supermolecular polyurethane elastomer 中国科学院兰州化学物理研究所 2024-01-19 CN disclosed
US-20230355843-A1 INJECTABLE CUSHIONING HYDROGELS SUPRA B B.V. (NL) 2023-11-09 US disclosed
US-20220153907-A1 DOUBLE DYNAMIC POLYMERS UNIVERSITÉ DE STRASBOURG (FR) 2022-05-19 US disclosed
CN-113604160-A Explosion-proof laser eavesdropping-proof protective film and preparation method thereof 三千新材料(苏州)有限公司 2021-11-05 CN disclosed
US-11045409-B2 Composition comprising a water-insoluble solid organic UV-screening agent and a compound capable of establishing hydrogen bonds L'OREAL (FR) 2021-06-29 US disclosed
CN-112867746-A Dual dynamic polymers 国家科学研究中心 2021-05-28 CN disclosed
CN-111848907-A Supermolecule polyurethane impact-resistant material containing multiple hydrogen bonds and preparation method thereof 上海交通大学 2020-10-30 CN disclosed
WO-2010002262-A1 HIGH FLOW SUPRAMOLECULAR COMPOUNDS SUPRAPOLIX B.V. (NL) 2010-01-07 WO disclosed
EP-2140858-A1 Cosmetic or dermatological composition comprising a compound capable of creating hydrogen bonds, and cosmetic treatment method L'Oréal (FR) 2010-01-06 EP disclosed
US-7622131-B2 Siloxane polymers with quadruple hydrogen bonding units SUPRAPOLIX B.V. (NL) 2009-11-24 US disclosed
US-7622131-B2 Siloxane polymers with quadruple hydrogen bonding units SUPRAPOLIX B.V. (NL) 2009-11-24 US disclosed
US-20090111930-A1 Supramolecular Ionomers SUPRAPOLIX B. V. 2009-04-30 US disclosed
US-20090111930-A1 Supramolecular Ionomers SUPRAPOLIX B. V. 2009-04-30 US disclosed
WO-2008063057-A2 SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS SUPRAPOLIX B.V. (NL) 2008-05-29 WO disclosed
US-20070093639-A1 Preparation of supramolecular polymer containing quadruple hydrogen bonding units in the polymer backbone SUPRAPOLIX B.V. 2007-04-26 US disclosed
US-20070093639-A1 Preparation of supramolecular polymer containing quadruple hydrogen bonding units in the polymer backbone SUPRAPOLIX B.V. 2007-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153907-A1 DOUBLE DYNAMIC POLYMERS PCNA, DCLRE1A, MRE11 HSD17B10 3401/4885CHEK1 475/4885KDM4E 2075/4885
US-11045409-B2 Composition comprising a water-insoluble solid organic UV-screening agent and a compound capable of establishing hydrogen bonds F2, F12, C1S HSD17B10 743/4885CHEK1 8/4885KDM4E 4786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.