Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965476 | 0.81 | HRH1 (0.42) | KDM4ESMN1; SMN2ALDH1A1LMNAHRH1 | |
| SCHEMBL9965421 | 0.80 | NSD2 (0.54) | KDM4ENSD2ALDH1A1KMT2ABRD4 | |
| SCHEMBL10174382 | 0.80 | MAPK3 (0.48) | KDM4ESMN1; SMN2NSD2ALDH1A1LMNA | |
| SCHEMBL9965412 | 0.80 | MLNR (0.47) | KDM4ESMN1; SMN2NSD2ALDH1A1LMNA | |
| SCHEMBL641004 | 0.79 | LMNA (0.65) | KDM4ESMN1; SMN2NSD2ALDH1A1LMNA | |
| SCHEMBL2884743 | 0.78 | MAPT (0.43) | KDM4ESMN1; SMN2NSD2ALDH1A1LMNA | |
| SCHEMBL641860 | 0.78 | NSD2 (0.51) | KDM4ESMN1; SMN2NSD2ALDH1A1KMT2A | |
| SCHEMBL28588875 | 0.77 | MAPT (0.48) | NSD2KMT2ABRD4MAPTEPHX2 | |
| SCHEMBL30352893 | 0.77 | EPHX2 (0.55) | NSD2ALDH1A1KMT2ABRD4MAPT | |
| SCHEMBL643978 | 0.77 | MAPT (0.48) | KDM4ESMN1; SMN2NSD2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-B1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | STERIX LTD (GB) | 2012-06-20 | — | — | EP | disclosed |