Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 10/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966408 | 0.87 | ALOX5AP (0.38) | HDAC1HDAC3HDAC7HDAC2HDAC8 | |
| SCHEMBL9966417 | 0.84 | IDO1 (0.43) | HDAC1HDAC3HDAC2ALOX5APIDO1 | |
| SCHEMBL9966182 | 0.81 | IDO1 (0.42) | ALOX5APIDO1MAP4K4 | |
| SCHEMBL9966467 | 0.81 | ALOX5AP (0.40) | ALOX5APIDO1MAP4K4 | |
| SCHEMBL9966472 | 0.80 | IDO1 (0.40) | HDAC1ALOX5APIDO1MAP4K4 | |
| SCHEMBL9966248 | 0.79 | IDO1 (0.36) | ALOX5APIDO1MAP4K4 | |
| SCHEMBL9966565 | 0.78 | ALOX5AP (0.36) | HDAC1ALOX5APIDO1MAP4K4 | |
| SCHEMBL9966523 | 0.77 | IDO1 (0.36) | ALOX5APIDO1MAP4K4 | |
| SCHEMBL16602682 | 0.77 | ALOX5AP (0.44) | HDAC1HDAC3HDAC7HDAC2HDAC8 | |
| SCHEMBL9966230 | 0.75 | ALOX5AP (0.41) | ALOX5APMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |