Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966308 | 0.97 | ALOX5AP (0.33) | IDO1ALOX5APGSK3BDYRK1A | |
| SCHEMBL9966277 | 0.90 | ALOX5AP (0.38) | ALOX5AP | |
| SCHEMBL9966365 | 0.85 | USP2 (0.33) | IDO1MAP4K4 | |
| SCHEMBL9966514 | 0.84 | MAP4K4 (0.40) | MAP4K4 | |
| SCHEMBL9966413 | 0.81 | RIPK1 (0.37) | ALOX5APMAP4K4 | |
| SCHEMBL9966449 | 0.80 | MAP4K4 (0.33) | MAP4K4 | |
| SCHEMBL9966408 | 0.80 | ALOX5AP (0.38) | IDO1ALOX5APMAP4K4 | |
| SCHEMBL9966486 | 0.80 | MAP4K4 (0.33) | MAP4K4 | |
| SCHEMBL9966182 | 0.79 | IDO1 (0.42) | IDO1ALOX5APMAP4K4 | |
| SCHEMBL9966391 | 0.79 | FFAR2 (0.33) | GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |