Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.38 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966417 | 0.91 | IDO1 (0.43) | ALOX5APIDO1HDAC1MAP4K4LMNA | |
| SCHEMBL9966252 | 0.87 | HDAC1 (0.41) | ALOX5APIDO1HDAC1MAP4K4HDAC3 | |
| SCHEMBL9966565 | 0.84 | ALOX5AP (0.36) | ALOX5APIDO1HDAC1MAP4K4LMNA | |
| SCHEMBL9966182 | 0.84 | IDO1 (0.42) | ALOX5APIDO1MAP4K4 | |
| SCHEMBL9966467 | 0.83 | ALOX5AP (0.40) | ALOX5APIDO1MAP4K4 | |
| SCHEMBL9966248 | 0.82 | IDO1 (0.36) | ALOX5APIDO1MAP4K4 | |
| SCHEMBL9966472 | 0.81 | IDO1 (0.40) | ALOX5APIDO1HDAC1MAP4K4 | |
| SCHEMBL9966523 | 0.80 | IDO1 (0.36) | ALOX5APIDO1MAP4K4 | |
| SCHEMBL9966230 | 0.78 | ALOX5AP (0.41) | ALOX5APMAP4K4 | |
| SCHEMBL9966308 | 0.78 | ALOX5AP (0.33) | ALOX5APIDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |