Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 13/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966507 | 0.83 | ALOX5AP (0.47) | ALOX5APMAP4K4IDO1HSD11B1 | |
| SCHEMBL10240437 | 0.82 | ALOX5AP (0.46) | ALOX5APMAP4K4HSD11B1 | |
| SCHEMBL1951679 | 0.81 | MAP4K4 (0.54) | ALOX5APMAP4K4LMNAMAPT | |
| SCHEMBL25422745 | 0.80 | ALOX5 (0.45) | MAP4K4PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL14315175 | 0.79 | HDAC1 (0.52) | ALOX5APIDO1LMNA | |
| SCHEMBL9966409 | 0.79 | HDAC1 (0.56) | ALOX5APIDO1LMNA | |
| SCHEMBL16592743 | 0.78 | ALOX5AP (0.48) | ALOX5APMAP4K4IDO1HSD11B1 | |
| SCHEMBL14325150 | 0.78 | HDAC1 (0.46) | ALOX5APMAP4K4IDO1 | |
| SCHEMBL9966281 | 0.78 | LMNA (0.60) | ALOX5APIDO1LMNA | |
| SCHEMBL9966446 | 0.78 | HDAC1 (0.52) | ALOX5APIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |