Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9942699 | 0.99 | LTA4H (0.54) | LTA4HTSHRL3MBTL1DRD3HRH3 | |
| SCHEMBL9942681 | 0.93 | LTA4H (0.52) | LTA4HHRH3OPRK1GCGRESR1 | |
| SCHEMBL9942753 | 0.92 | LTA4H (0.53) | LTA4HHRH3OPRK1GCGRESR1 | |
| SCHEMBL9966796 | 0.92 | LTA4H (0.53) | LTA4HHRH3OPRK1GCGRESR1 | |
| Hydrochloric Acid SCHEMBL9940187 | 0.91 | LTA4H (0.52) | LTA4HHRH3OPRK1GCGRESR1 | |
| SCHEMBL9936264 | 0.91 | LTA4H (0.54) | LTA4HTSHR | |
| SCHEMBL9966794 | 0.90 | KDM4E (0.48) | LTA4HHRH3OPRK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9940208 | 0.89 | KDM4E (0.47) | LTA4HHRH3OPRK1KDM4E | |
| SCHEMBL9967050 | 0.88 | ESR1 (0.56) | LTA4HESR1ESR2 | |
| SCHEMBL9967005 | 0.87 | LTA4H (0.58) | LTA4HDRD3HRH3OPRK1GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |