Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310756 | 1.00 | ALOX5 (0.42) | ALOX5ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL14012089 | 0.86 | ALDH1A1 (0.34) | ALOX5ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL13978600 | 0.85 | TSHR (0.39) | ALDH1A1HPGDCYP2C9TSHRSMN1; SMN2 | |
| SCHEMBL17149563 | 0.84 | ALOX5 (0.38) | ALOX5ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL5264377 | 0.80 | ALOX5 (0.44) | ALOX5ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL13369376 | 0.80 | ALOX5 (0.41) | ALOX5ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL22931231 | 0.79 | ALOX5 (0.38) | ALOX5ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL14035043 | 0.79 | ALOX5 (0.39) | ALOX5ALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL18677511 | 0.79 | TSHR (0.35) | ALDH1A1HPGDTSHRSMN1; SMN2TP53 | |
| SCHEMBL12260256 | 0.78 | ALOX5 (0.40) | ALOX5ALDH1A1HPGDKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115477-A1 | BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | NOVARTIS AG (CH) | 2022-06-02 | — | — | WO | disclosed |
| WO-2012080520-A1 | ENVIRONMENTAL ANTI-CORROSION ADDITIVES BASED ON POLY(ALKYL THIOPHENE ACETATES) WHICH CAN BE EASILY DISPERSED IN PRIMING PAINTS FOR METAL SURFACES | UNIVERSITAT POLITÈCNICA DE CATALUNYA (ES) | 2012-06-21 | — | — | WO | disclosed |
| US-20070021494-A1 | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION AND PHARMACOPEIA, INC. | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021494-A1 | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | CCR1, ACKR3, CXCR1 | ALOX5 428/4885ALDH1A1 1019/4885HPGD 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.