Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079157 | 0.87 | GFER (0.78) | HPGDMAPTHSD17B10ALDH1A1PKM | |
| SCHEMBL19097995 | 0.85 | HPGD (0.73) | HPGDMAPTHSD17B10ALDH1A1PKM | |
| SCHEMBL9968014 | 0.85 | HPGD (0.74) | HPGDMAPTALDH1A1PKMKMT2A | |
| SCHEMBL9968020 | 0.85 | HPGD (0.74) | HPGDMAPTHSD17B10ALDH1A1PKM | |
| SCHEMBL9968019 | 0.85 | LMNA (0.84) | HPGDMAPTALDH1A1PKMKMT2A | |
| SCHEMBL27180046 | 0.85 | RAB9A (0.72) | HPGDMAPTHSD17B10ALDH1A1PKM | |
| SCHEMBL4881954 | 0.84 | HPGD (0.72) | HPGDMAPTHSD17B10ALDH1A1PKM | |
| SCHEMBL12010887 | 0.83 | KMT2A (0.72) | HPGDMAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL30927019 | 0.82 | MAPT (0.77) | HPGDMAPTHSD17B10ALDH1A1PKM | |
| SCHEMBL27180119 | 0.82 | MAPT (0.77) | HPGDMAPTHSD17B10ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140088187-A1 | ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2014-03-27 | — | — | US | disclosed |
| WO-2012082862-A2 | ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088187-A1 | ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | AR, NR5A1, ESRRB | HPGD 917/4885MAPT 4552/4885HSD17B10 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.