⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891059 | 0.73 | — | — | |
| SCHEMBL9968031 | 0.72 | — | — | |
| SCHEMBL3397260 | 0.71 | — | — | |
| SCHEMBL16124294 | 0.70 | — | — | |
| SCHEMBL11443334 | 0.67 | TSHR (0.48) | — | |
| SCHEMBL874362 | 0.67 | TSHR (0.48) | — | |
| SCHEMBL89170 | 0.63 | — | — | |
| SCHEMBL7334812 | 0.61 | — | — | |
| Phosphoric Acid SCHEMBL16110763 | 0.59 | ALDH1A1 (0.39) | — | |
| SCHEMBL193555 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802874-B2 | Trihydroxy polyunsaturated eicosanoid derivatives | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130296590-A1 | TRIHYDROXY POLYUNSATURATED EICOSANOID DERIVATIVES | NATIONAL INSTITUTES OF HEALTH | 2013-11-07 | — | — | US | disclosed |
| US-8481772-B2 | Trihydroxy polyunsaturated eicosanoid derivatives | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-07-09 | — | — | US | disclosed |
| US-8461201-B2 | Trihydroxy polyunsaturated eicosanoid derivatives | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-06-11 | — | — | US | disclosed |
| US-20120157700-A1 | TRIHYDROXY POLYUNSATURATED EICOSANOID DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-06-21 | — | — | US | disclosed |
| US-20110237545-A1 | TRIHYDROXY POLYUNSATURATED EICOSANOID DERIVATIVES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-09-29 | — | — | US | disclosed |
| US-7902257-B2 | Trihydroxy polyunsaturated eicosanoid | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-03-08 | — | — | US | disclosed |
| US-20090291916-A1 | Trihydroxy Polyunsaturated Eicosanoid | UNIVERSITY OF SOUTHERN CALIFORNIA | 2009-11-26 | — | — | US | disclosed |
| US-7582785-B2 | Trihydroxy polyunsaturated eicosanoid derivatives | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-09-01 | — | — | US | disclosed |