Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968071 | 0.88 | AAK1 (0.30) | AAK1 | |
| SCHEMBL9968129 | 0.78 | MAOA (0.39) | AAK1ADORA3ADORA2AROCK2MAPT | |
| SCHEMBL9968079 | 0.77 | ADORA3 (0.36) | AAK1ADORA3ADORA2AROCK2DYRK1A | |
| SCHEMBL9968104 | 0.76 | — | — | |
| SCHEMBL1609661 | 0.74 | ADORA3 (0.54) | ADORA3ADORA2AROCK2DYRK1ANFATC1 | |
| SCHEMBL9968095 | 0.73 | TOP2A (0.38) | AAK1ADORA3ADORA2AROCK2MAPT | |
| SCHEMBL9968107 | 0.70 | ADORA3 (0.41) | AAK1ADORA3ADORA2AROCK2DYRK1A | |
| SCHEMBL12183422 | 0.70 | HASPIN (0.41) | DYRK1AMAPTHASPIN | |
| SCHEMBL14659349 | 0.69 | AAK1 (0.47) | AAK1ADORA3ADORA2AMAPTHASPIN | |
| SCHEMBL12464502 | 0.68 | ADORA3 (0.50) | AAK1ADORA3ADORA2AROCK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120153817-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120153817-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |