SCHEMBL9968147

SCHEMBL9968147

CC(C)(C)Cc1cc2c3cc(C(C)(C)c4ccc5c(c4)c4cc(CC(C)(C)C)ncc4n5-c4ccccc4)ccc3n(-c3ccccc3)c2cn1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ATM Q13315 1/20 0.34
PPARG P37231 4/20 0.33
ALDH1A1 P00352 3/20 0.31
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GRN P28799 1/20 0.31
SORT1 Q99523 1/20 0.31
PPARA Q07869 2/20 0.31
DNMT1 P26358 3/20 0.30
MAT2A P31153 1/20 0.30
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21085499 0.87 KDM4E (0.49) KDM4EL3MBTL1ATMPPARGALDH1A1
SCHEMBL9968143 0.83 KDM4E (0.33) KDM4EL3MBTL1ATMALDH1A1MEN1
SCHEMBL9968240 0.78 PPARG (0.37) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL9968202 0.77 L3MBTL1 (0.37) KDM4EL3MBTL1ATMPPARGALDH1A1
SCHEMBL13589177 0.75 ESR1 (0.44) KDM4EL3MBTL1ATMPPARGALDH1A1
SCHEMBL9968261 0.75 PPARG (0.35) KDM4EL3MBTL1ATMPPARGPPARA
SCHEMBL9968176 0.74 KDM4E (0.33) KDM4EL3MBTL1ATMPPARG
SCHEMBL31621190 0.73 L3MBTL1 (0.52) KDM4EL3MBTL1ATMPPARGALDH1A1
SCHEMBL13146817 0.73 L3MBTL1 (0.52) KDM4EL3MBTL1ATMPPARGALDH1A1
SCHEMBL14649307 0.73 KDM4E (0.55) KDM4EL3MBTL1ATMPPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed