Sugi Predict

Sugi Predict / Compounds / SCHEMBL996850

SCHEMBL996850

SCHEMBL996850

O=S(=O)(O)c1ccc(P(c2ccccc2)c2ccc(S(=O)(=O)O)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.65
▸ SMN1; SMN2 Q16637 1/20 0.65
▸ CYP2D6 P10635 2/20 0.55
▸ POLB P06746 1/20 0.55
▸ TDP1 Q9NUW8 3/20 0.55
▸ CYP3A4 P08684 1/20 0.55
▸ ESR1 P03372 2/20 0.54
▸ ESR2 Q92731 2/20 0.54
▸ LMNA P02545 1/20 0.50
▸ ALDH1A1 P00352 4/20 0.48
▸ NT5E P21589 1/20 0.48
▸ SNCA P37840 1/20 0.42
▸ MAPK1 P28482 1/20 0.39
▸ HTR6 P50406 1/20 0.39
▸ HSD17B10 Q99714 2/20 0.38
▸ NAPRT Q6XQN6 1/20 0.38
▸ PTPRA P18433 1/20 0.37
▸ PTPRB P23467 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718256 1.00 TSHR (0.65) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL8773415 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
Water SCHEMBL570669 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
Water SCHEMBL30394765 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
Potassium SCHEMBL1450612 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL6568428 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL8145540 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL301148 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL6569261 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
Water SCHEMBL1238257 0.96 TSHR (0.60) TSHRSMN1; SMN2CYP2D6POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731570-A2 GAMMA-GRAPHYNE AND METHODS OF FABRICATION CASE WESTERN RESERVE UNIVERSITY (US) 2026-04-29 — — EP claimed
WO-2024264047-A2 GAMMA-GRAPHYNE AND METHODS OF FABRICATION CASE WESTERN RESERVE UNIVERSITY (US) 2024-12-26 — — WO claimed
US-20240216521-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES IMMUNOGEN INC (US) 2024-07-04 — — US claimed
CN-115931786-B Double-signal sensor for detecting organophosphorus pesticide and preparation method and application thereof 南京农业大学 2024-03-15 — — CN claimed
US-11833214-B2 Methods of preparing cell-binding agent-drug conjugates IMMUNOGEN, INC. (US) 2023-12-05 — — US claimed
CN-111257457-B Analysis method for determining metal sulfide nanoparticles in water 广州大学 2022-05-24 — — CN claimed
EP-3941527-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES ImmunoGen, Inc. (US) 2022-01-26 — — EP claimed
CN-113631194-A Method for preparing cell-binding agent-drug conjugates 伊缪诺金公司 2021-11-09 — — CN claimed
CN-113059177-A Nano particle with gold/silver/gold core-shell structure and synthesis method thereof 江苏师范大学 2021-07-02 — — CN claimed
US-20200405874-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES IMMUNOGEN, INC. 2020-12-31 — — US claimed
WO-1996033969-A1 METHOD OF HYDROCYANATING UNSATURATED NITRILES INTO DINITRILES RHONE-POULENC CHIMIE (FR) 1996-10-31 — — WO claimed
EP-0722432-A1 METHOD FOR PREPARING OF MONO OR DI-2-SUBSTITUTED CYCLOPENTANONE RHONE-POULENC AGROCHIMIE (FR) 1996-07-24 — — EP claimed
EP-0715890-A1 Electrochemical preparation process of transition metal and phosphine containing catalysts RHONE-POULENC FIBER & RESIN INTERMEDIATES (FR) 1996-06-12 — — EP claimed
US-5488129-A CATALYST SYSTEM CONTAINING TRANSITION METAL COMPOUND, SULFONATED PHOSPHINE, LEWIS ACID RHONE-POULENC CHIMIE (FR) 1996-01-30 — — US claimed
US-5486643-A Isomerization of 2-methyl-3-butenenitrile RHONE-POULENC CHIMIE (FR) 1996-01-23 — — US claimed
EP-0650959-A1 Hydrocyanation process of unsatured nitriles into dinitriles RHONE-POULENC FIBER & RESIN INTERMEDIATES (FR) 1995-05-03 — — EP claimed
WO-1995009830-A1 METHOD FOR PREPARING OF MONO OR DI-2-SUBSTITUTED CYCLOPENTANONE RHONE POULENC AGROCHIMIE (FR) 1995-04-13 — — WO claimed
EP-0647619-A1 Process for the preparation of 2-methyl-3-butene nitrile RHONE-POULENC FIBER & RESIN INTERMEDIATES (FR) 1995-04-12 — — EP claimed
US-RE31812-E TO ALDEHYDES IN PRESENCE OF CATALYTIC SYSTEM CONTAINING RHODIUM AND SULFONATED ARYL PHOSPHINE COMPOUND RHONE-POULENC INDUSTRIES (FR) 1985-01-22 — — US claimed
US-4248802-A Catalytic hydroformylation of olefins RHONE-POULENC INDUSTRIES (FR) 1981-02-03 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11833214-B2 Methods of preparing cell-binding agent-drug conjugates EPCAM, CD2BP2, XPA TSHR 2222/4885SMN1; SMN2 3191/4885CYP2D6 2255/4885
US-20200405874-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES EPCAM, CD2BP2, XPA TSHR 2222/4885SMN1; SMN2 3191/4885CYP2D6 2255/4885
US-20240216521-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES EPCAM, CD2BP2, XPA TSHR 2222/4885SMN1; SMN2 3191/4885CYP2D6 2255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.