SCHEMBL718256

SCHEMBL718256

O=S(=O)(O)c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
CYP2D6 P10635 2/20 0.55
POLB P06746 1/20 0.55
TDP1 Q9NUW8 3/20 0.55
CYP3A4 P08684 1/20 0.55
ESR1 P03372 2/20 0.54
ESR2 Q92731 2/20 0.54
LMNA P02545 1/20 0.50
ALDH1A1 P00352 4/20 0.48
NT5E P21589 1/20 0.48
SNCA P37840 1/20 0.42
MAPK1 P28482 1/20 0.39
HTR6 P50406 1/20 0.39
HSD17B10 Q99714 2/20 0.38
NAPRT Q6XQN6 1/20 0.38
PTPRA P18433 1/20 0.37
PTPRB P23467 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996850 1.00 TSHR (0.65) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL8773415 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
Water SCHEMBL570669 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
Water SCHEMBL30394765 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
Potassium SCHEMBL1450612 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL6568428 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL8145540 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL301148 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
SCHEMBL6569261 0.98 TSHR (0.62) TSHRSMN1; SMN2CYP2D6POLBTDP1
Water SCHEMBL1238257 0.96 TSHR (0.60) TSHRSMN1; SMN2CYP2D6POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731570-A2 GAMMA-GRAPHYNE AND METHODS OF FABRICATION CASE WESTERN RESERVE UNIVERSITY (US) 2026-04-29 EP claimed
US-12251401-B2 Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2025-03-18 US claimed
WO-2024264047-A2 GAMMA-GRAPHYNE AND METHODS OF FABRICATION CASE WESTERN RESERVE UNIVERSITY (US) 2024-12-26 WO claimed
EP-4426727-A2 SPECIFIC CONJUGATION OF AN ANTIBODY Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 EP claimed
CN-117980327-A Specific coupling of antibodies 杭州多禧生物科技有限公司 2024-05-03 CN claimed
US-20240050469-A1 Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2024-02-15 US claimed
US-11779598-B2 Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates THE FLORIDA INTERNATIONAL UNIVERISTY BOARD OF TRUSTEES (US) 2023-10-10 US claimed
WO-2022078524-A4 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-12-08 WO claimed
WO-2022078524-A2 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-04-21 WO claimed
US-20220047628-A1 Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2022-02-17 US claimed
EP-0722432-A1 METHOD FOR PREPARING OF MONO OR DI-2-SUBSTITUTED CYCLOPENTANONE RHONE-POULENC AGROCHIMIE (FR) 1996-07-24 EP claimed
EP-0715890-A1 Electrochemical preparation process of transition metal and phosphine containing catalysts RHONE-POULENC FIBER & RESIN INTERMEDIATES (FR) 1996-06-12 EP claimed
US-5488129-A CATALYST SYSTEM CONTAINING TRANSITION METAL COMPOUND, SULFONATED PHOSPHINE, LEWIS ACID RHONE-POULENC CHIMIE (FR) 1996-01-30 US claimed
US-5486643-A Isomerization of 2-methyl-3-butenenitrile RHONE-POULENC CHIMIE (FR) 1996-01-23 US claimed
CN-1108643-A Method for hydrocyanation of unsatured nitrile into dinitrile RHONE POULENC CHIMIE (FR) 1995-09-20 CN claimed
EP-0650959-A1 Hydrocyanation process of unsatured nitriles into dinitriles RHONE-POULENC FIBER & RESIN INTERMEDIATES (FR) 1995-05-03 EP claimed
WO-1995009830-A1 METHOD FOR PREPARING OF MONO OR DI-2-SUBSTITUTED CYCLOPENTANONE RHONE POULENC AGROCHIMIE (FR) 1995-04-13 WO claimed
EP-0647619-A1 Process for the preparation of 2-methyl-3-butene nitrile RHONE-POULENC FIBER & RESIN INTERMEDIATES (FR) 1995-04-12 EP claimed
US-RE31812-E TO ALDEHYDES IN PRESENCE OF CATALYTIC SYSTEM CONTAINING RHODIUM AND SULFONATED ARYL PHOSPHINE COMPOUND RHONE-POULENC INDUSTRIES (FR) 1985-01-22 US claimed
US-4248802-A Catalytic hydroformylation of olefins RHONE-POULENC INDUSTRIES (FR) 1981-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12251401-B2 Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates POLR1C, ZC3HAV1, HELZ TSHR 3780/4885SMN1; SMN2 4313/4885CYP2D6 2113/4885
US-20220047628-A1 Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates POLR1C, ZC3HAV1, HELZ TSHR 3780/4885SMN1; SMN2 4313/4885CYP2D6 2113/4885
US-20240050469-A1 Synthesis and Antimicrobial Uses of Dinuclear Silver(I) Pyrazolates POLR1C, ZC3HAV1, HELZ TSHR 3780/4885SMN1; SMN2 4313/4885CYP2D6 2113/4885
US-11779598-B2 Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates POLR1C, ZC3HAV1, HELZ TSHR 3780/4885SMN1; SMN2 4313/4885CYP2D6 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.