Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584174 | 0.77 | KDM4E (0.59) | KMT2AKDM4EALDH1A1MEN1NR1H3 | |
| SCHEMBL11862277 | 0.76 | KDM4E (0.74) | KMT2AKDM4EALDH1A1MEN1NR1H3 | |
| SCHEMBL4726090 | 0.73 | KMT2A (0.61) | KMT2AKDM4EALDH1A1MEN1NR1H3 | |
| SCHEMBL2550387 | 0.68 | NR1H3 (0.81) | KMT2AKDM4EALDH1A1MEN1NR1H3 | |
| SCHEMBL31050182 | 0.68 | KMT2A (0.64) | KMT2AKDM4EALDH1A1MEN1NR1H3 | |
| SCHEMBL3408445 | 0.68 | KMT2A (0.66) | KMT2AKDM4EALDH1A1MEN1NR1H3 | |
| SCHEMBL4649471 | 0.67 | KMT2A (0.78) | KMT2AALDH1A1MEN1NR1H3GAA | |
| SCHEMBL18874610 | 0.67 | KMT2A (0.56) | KMT2AKDM4EALDH1A1MEN1NR1H3 | |
| SCHEMBL25918284 | 0.67 | NR1H3 (0.64) | KMT2AKDM4EALDH1A1MEN1NR1H3 | |
| SCHEMBL27264218 | 0.67 | KMT2A (0.53) | KMT2AKDM4EALDH1A1MEN1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963276-B1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2012-06-20 | — | — | EP | disclosed |