Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584174 | 0.83 | KDM4E (0.59) | KMT2APPARGNR1H3MEN1KDM4E | |
| SCHEMBL11862277 | 0.80 | KDM4E (0.74) | KMT2APPARGNR1H3MEN1KDM4E | |
| 1,4-Diisopentoxybenzene SCHEMBL2846102 | 0.75 | TDP1 (0.79) | KMT2AALDH1A1TDP1GAARAB9A | |
| SCHEMBL2550387 | 0.74 | NR1H3 (0.81) | KMT2ANR1H3MEN1KDM4EALDH1A1 | |
| SCHEMBL31050182 | 0.73 | KMT2A (0.64) | KMT2APPARGNR1H3MEN1KDM4E | |
| SCHEMBL3408445 | 0.73 | KMT2A (0.66) | KMT2ANR1H3MEN1KDM4EALDH1A1 | |
| SCHEMBL2209458 | 0.73 | L3MBTL1 (0.76) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL3595826 | 0.73 | LTA4H (0.57) | — | |
| SCHEMBL9968683 | 0.73 | KMT2A (0.50) | KMT2APPARGNR1H3MEN1PLA2G1B | |
| SCHEMBL195569 | 0.73 | TDP1 (0.64) | ALDH1A1HPGDTDP1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029168-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |