Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703490 | 0.85 | ACHE (0.48) | ACHEKMT2AL3MBTL1LMNAHSP90AA1 | |
| SCHEMBL4618588 | 0.84 | ACHE (0.74) | ACHEKMT2AALDH1A1MAPK1TSHR | |
| SCHEMBL1410581 | 0.84 | ALDH1A1 (0.74) | ACHEKMT2AALDH1A1MAPK1HDAC8 | |
| M-Xylene SCHEMBL10416113 | 0.83 | ACHE (0.67) | ACHEKMT2AALDH1A1MAPK1PARP1 | |
| M-Xylene SCHEMBL27858710 | 0.83 | ACHE (0.67) | ACHEKMT2AALDH1A1MAPK1PARP1 | |
| M-Xylene SCHEMBL27875113 | 0.83 | ACHE (0.67) | ACHEKMT2AALDH1A1MAPK1PARP1 | |
| SCHEMBL841739 | 0.82 | ALDH1A1 (0.44) | ACHEALDH1A1MAPK1TSHRTDP1 | |
| SCHEMBL27310696 | 0.82 | ALDH1A1 (0.44) | ACHEALDH1A1MAPK1TSHRTDP1 | |
| M-Xylene SCHEMBL28189 | 0.82 | — | — | |
| M-Xylene SCHEMBL891494 | 0.82 | ACHE (1.00) | ACHEALDH1A1MAPK1PARP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897088-B | Phenylalanine derivative containing N- (2-oxoethyl) benzene sulfonamide and preparation method and application thereof | 山东大学 | 2022-06-17 | — | — | CN | claimed |
| CN-109516987-B | Preparation method of avibactam intermediate | 江西富祥药业股份有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-102993435-B | Star copolymer of aniline oligomer and polyethylene glycol and preparation method thereof | UNIV BEIHANG | 2014-08-27 | — | — | CN | claimed |
| CN-102993435-A | Star copolymer of aniline oligomer and polyethylene glycol and preparation method thereof | UNIV BEIHANG | 2013-03-27 | — | — | CN | claimed |
| CN-109897088-B | Phenylalanine derivative containing N- (2-oxoethyl) benzene sulfonamide and preparation method and application thereof | 山东大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-111187188-A | Synthesis method of substituted thiophenol | 普济生物科技（台州）有限公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-104678028-B | The pre-treatment of biological original amine neurotransmitters and detection method and detection kit | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-08-15 | — | — | CN | disclosed |
| CN-106279041-A | Phenyl pyrimidine derivative and its production and use | 四川思睿博生物科技有限公司 | 2017-01-04 | — | — | CN | disclosed |
| EP-2456435-B1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | UNIV LELAND STANFORD JUNIOR (US) | 2015-06-24 | — | — | EP | disclosed |
| CN-102993435-B | Star copolymer of aniline oligomer and polyethylene glycol and preparation method thereof | UNIV BEIHANG | 2014-08-27 | — | — | CN | disclosed |
| CN-103596925-A | Benzocycloheptene acetic acids | HOFFMANN LA ROCHE | 2014-02-19 | — | — | CN | disclosed |
| CN-102531978-B | Preparation method of thiophenol | UNIV ZHEJIANG | 2013-12-18 | — | — | CN | disclosed |
| US-4022674-A | Photopolymerizable compounds and compositions comprising the product of the reaction of a monomeric ester and a polycarboxy-substituted benzophenone | SUN CHEMICAL CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-4008138-A | Photopolymerizable compounds and compositions comprising the product of the reaction of a monocarboxy-substituted benzophenone with a resin | SUN CHEMICAL CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |
| US-4004998-A | Photopolymerizable compounds and compositions comprising the product of the reaction of a hydroxy-containing ester and a monocarboxy-substituted benzophenone | SUN CHEMICAL CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |
| US-3988228-A | Photopolymerizable polymeric compositions containing halogen containing aromatic ketones | EASTMAN KODAK COMPANY (US) | 1976-10-26 | — | — | US | disclosed |
| US-3966573-A | HALOGENATED HYDROCARBONS, CARBONYL COMPOUNDS, ORGANO-NITROGEN, PHOSPHOROUS, ARSENIC, BISMUTH, OR ANTIMONY COMPOUNDS | SUN CHEMICAL CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
| US-3962056-A | MOLDING, COATING | EASTMAN KODAK COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3962055-A | MOLDING, COATING | EASTMAN KODAK COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3933682-A | Photopolymerization co-initiator systems | SUN CHEMICAL CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |