Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20067758 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MEN1MPIKMT2AHPGD | |
| SCHEMBL27402687 | 0.83 | MAPK1 (0.41) | HSD17B2HSD17B1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL27404620 | 0.82 | MAPK1 (0.43) | HSD17B2HSD17B1ALDH1A1MEN1MPI | |
| SCHEMBL27402690 | 0.80 | PDE5A (0.39) | HSD17B2HSD17B1ALDH1A1MEN1MPI | |
| SCHEMBL23346051 | 0.79 | APP (0.42) | APPHSD17B2HSD17B1CYP1A2GRM8 | |
| SCHEMBL10030801 | 0.79 | CYP1A2 (0.40) | APPHSD17B2HSD17B1CYP1A2GRM8 | |
| SCHEMBL9970223 | 0.79 | APP (0.49) | APPCYP1A2CYP2C9ALDH1A1CYP2E1 | |
| SCHEMBL27404621 | 0.79 | PDE5A (0.40) | ALDH1A1MEN1MPIKMT2AHPGD | |
| SCHEMBL27402779 | 0.79 | AAK1 (0.36) | APPHSD17B2HSD17B1ALDH1A1MEN1 | |
| SCHEMBL9970217 | 0.78 | ESR2 (0.39) | HSD17B2HSD17B1ALDH1A1MEN1MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202584-B2 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2012-06-19 | — | — | US | disclosed |
| EP-2239310-A1 | Liquid crystal medium and liquid crystal display | Merck Patent GmbH (DE) | 2010-10-13 | — | — | EP | disclosed |
| US-20100252777-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-10-07 | — | — | US | disclosed |