Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20067758 | 0.92 | ALDH1A1 (0.41) | ESR2ESR1ALDH1A1NPC1HSD17B10 | |
| SCHEMBL9970222 | 0.79 | PTGS2 (0.36) | ESR2ESR1ALDH1A1NPC1HSD17B10 | |
| SCHEMBL22872130 | 0.78 | ESR2 (0.35) | ESR2ESR1ALDH1A1HPGDHSD17B1 | |
| SCHEMBL9970218 | 0.78 | APP (0.42) | ALDH1A1MEN1MPIKMT2AHPGD | |
| SCHEMBL13021502 | 0.75 | ESR2 (0.39) | ESR2ESR1ALDH1A1NPC1HSD17B10 | |
| SCHEMBL12023277 | 0.75 | POLB (0.38) | PTGS2HPGDNOS3NOS1NOS2 | |
| SCHEMBL18069659 | 0.75 | POLB (0.38) | PTGS2HPGDNOS3NOS1NOS2 | |
| SCHEMBL17657409 | 0.75 | MEN1 (0.31) | ALDH1A1MEN1KMT2A | |
| SCHEMBL25078679 | 0.74 | NISCH (0.44) | ESR2ESR1ALDH1A1NPC1HSD17B10 | |
| SCHEMBL22872118 | 0.74 | ESR2 (0.33) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239310-B1 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| US-8202584-B2 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2012-06-19 | — | — | US | disclosed |
| EP-2239310-A1 | Liquid crystal medium and liquid crystal display | Merck Patent GmbH (DE) | 2010-10-13 | — | — | EP | disclosed |
| US-20100252777-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-10-07 | — | — | US | disclosed |