Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9964966 | 0.86 | KDM4E (0.43) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9964984 | 0.74 | ROCK2 (0.40) | KDM4EHTR7HTR1BESR1DRD2 | |
| SCHEMBL9965024 | 0.74 | KDM4E (0.38) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL23640283 | 0.70 | KDM4E (0.51) | KDM4EGAAHTR7HTR1BESR1 | |
| SCHEMBL6461121 | 0.69 | AHR (0.50) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9964962 | 0.68 | KDM4E (0.45) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL9970787 | 0.68 | POLB (0.49) | KDM4EGAAMEN1POLBMAPT | |
| SCHEMBL18949728 | 0.67 | HTR1B (0.63) | KDM4EMEN1KMT2AHTR7HTR1B | |
| SCHEMBL14000157 | 0.66 | KDM4E (0.56) | KDM4EGAAPOLBHTR7HTR1B | |
| SCHEMBL17147252 | 0.66 | KDM4E (0.62) | KDM4EMAPTPKMHTR7HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080321-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |