SCHEMBL17147252

SCHEMBL17147252

Cc1cc(OCCN(C)C)c(C)cc1OCCN(C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.62
CYP1A2 P05177 2/20 0.54
CYP2D6 P10635 2/20 0.54
CHRNA4 P43681 2/20 0.54
ADRA2A P08913 1/20 0.54
PKM P14618 1/20 0.54
ADRA2B P18089 1/20 0.54
ADRA2C P18825 1/20 0.54
ADRA1D P25100 1/20 0.54
HTR2C P28335 1/20 0.54
ADRA1A P35348 1/20 0.54
HRH1 P35367 1/20 0.54
ADRA1B P35368 1/20 0.54
DRD3 P35462 1/20 0.54
OPRK1 P41145 1/20 0.54
HIF1A Q16665 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.53
BLM P54132 1/20 0.53
HTR7 P34969 3/20 0.50
ESR1 P03372 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16372582 0.89 KDM4E (0.53) KDM4ECYP1A2CYP2D6CHRNA4ADRA2A
SCHEMBL13602319 0.85 KDM4E (0.53) KDM4ECYP1A2CYP2D6CHRNA4ADRA2A
SCHEMBL13663257 0.82 KDM4E (0.50) KDM4ECYP1A2CYP2D6CHRNA4ADRA2A
SCHEMBL14000157 0.82 KDM4E (0.56) KDM4ECYP1A2CYP2D6ADRA1ASMN1; SMN2
SCHEMBL13696489 0.81 KDM4E (0.49) KDM4ECYP1A2CYP2D6CHRNA4ADRA2A
SCHEMBL7524809 0.81 KDM4E (0.53) KDM4ECHRNA4SMN1; SMN2HTR7MAPT
SCHEMBL25783924 0.80 HTR7 (0.50) KDM4ECYP1A2CYP2D6CHRNA4ADRA2A
SCHEMBL18773673 0.79 KDM4E (0.52) KDM4ECHRNA4SMN1; SMN2HTR7MAPT
SCHEMBL18773703 0.79 KDM4E (0.64) KDM4ESMN1; SMN2ESR1MAPTALDH1A1
SCHEMBL15062039 0.79 KDM4E (0.51) KDM4ECYP1A2CYP2D6HTR2CSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9935269-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2018-04-03 US disclosed
US-20150287927-A1 ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed