Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177620 | 0.82 | CYP1A2 (0.38) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL9970942 | 0.76 | MAPT (0.46) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP2D6 | |
| SCHEMBL12051560 | 0.69 | SOS1 (0.35) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL21177942 | 0.68 | CYP1A2 (0.36) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL21177290 | 0.67 | CYP1A2 (0.36) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL15711332 | 0.66 | TSHR (0.44) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL7717522 | 0.65 | CYP1A2 (0.50) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL27912703 | 0.65 | MAPT (0.39) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 | |
| SCHEMBL2516413 | 0.65 | CYP1A2 (0.43) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL27685777 | 0.63 | CYP1A2 (0.42) | CYP1A2ALDH1A1CYP2C19HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202876-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2012-06-19 | — | — | US | disclosed |
| US-20100029605-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029605-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | FYN, ABL2, LCK | CYP1A2 4008/4885ALDH1A1 3998/4885CYP2C19 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.