Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757521 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL4209048 | 0.83 | TDP1 (0.57) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL11209949 | 0.83 | TDP1 (0.57) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL3382989 | 0.83 | ALDH1A1 (0.48) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL14775220 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL21450800 | 0.80 | CYP19A1 (0.45) | ALDH1A1LMNATDP1MEN1KMT2A | |
| SCHEMBL18809216 | 0.80 | SMN1; SMN2 (0.41) | LMNACES2CES1SMN1; SMN2MAOB | |
| SCHEMBL14775222 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL9964954 | 0.78 | SMN1; SMN2 (0.35) | ALDH1A1LMNACES2CES1TDP1 | |
| SCHEMBL14099145 | 0.77 | CES2 (0.55) | ALDH1A1LMNACES2CES1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082433-A1 | PREPARATION OF SULFONATED POLYOXADIAZOLE POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-21 | — | — | WO | disclosed |