Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8652449 | 1.00 | CYP19A1 (0.36) | CYP19A1MAPTAKR1C3AKR1C1GPR35 | |
| SCHEMBL1416850 | 0.79 | — | — | |
| SCHEMBL17200865 | 0.78 | ALDH1A1 (0.46) | CYP19A1 | |
| SCHEMBL2010694 | 0.74 | — | — | |
| SCHEMBL218876 | 0.72 | CYP19A1 (0.36) | CYP19A1MAPTAKR1C3AKR1C1 | |
| SCHEMBL5057907 | 0.72 | CYP19A1 (0.36) | CYP19A1MAPTAKR1C3AKR1C1 | |
| SCHEMBL28451456 | 0.72 | CYP19A1 (0.36) | CYP19A1MAPTAKR1C3AKR1C1 | |
| SCHEMBL2000716 | 0.71 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL5961832 | 0.71 | MAPT (0.35) | CYP19A1MAPTAKR1C3AKR1C1 | |
| Acetic Acid SCHEMBL9517248 | 0.69 | CYP19A1 (0.38) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7876403-B2 | Optical compensation film, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2011-01-25 | — | — | US | disclosed |
| US-20090180059-A1 | OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-07-16 | — | — | US | disclosed |
| WO-2007064029-A1 | OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2007-06-07 | — | — | WO | disclosed |
| EP-0202316-A1 | METHYL SUBSTITUTED BICYCLO AD2.2.1 BD HEPTANE/HEPTENE METHYLOL DERIVATIVES AND THEIR USE AS SCENTS | Dragoco Gerberding & Co. GmbH (DE) | 1986-11-26 | — | — | EP | disclosed |
| WO-1986003191-A1 | METHYL SUBSTITUTED BICYCLO AD2.2.1 BD HEPTANE/HEPTENE METHYLOL DERIVATIVES AND THEIR USE AS SCENTS | DRAGOCO GERBERDING & CO. GMBH (DE) | 1986-06-05 | — | — | WO | disclosed |