Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5075352 | 1.00 | ATM (0.54) | ATMELANECTSKCTRB1PRTN3 | |
| SCHEMBL1764625 | 0.85 | ATM (0.57) | ATMELANECTSKCTRB1PRTN3 | |
| SCHEMBL6926649 | 0.85 | ATM (0.57) | ATMELANECTSKCTRB1PRTN3 | |
| SCHEMBL9312050 | 0.84 | ELANE (0.50) | ATMELANECTSKCTRB1PRTN3 | |
| SCHEMBL14704026 | 0.80 | ATM (0.61) | ATMELANECTSKCTRB1PRTN3 | |
| SCHEMBL12942877 | 0.80 | ATM (0.61) | ATMELANECTSKCTRB1PRTN3 | |
| SCHEMBL12906609 | 0.80 | ATM (0.61) | ATMELANECTSKCTRB1PRTN3 | |
| SCHEMBL6841166 | 0.80 | ATM (0.61) | ATMELANECTSKCTRB1PRTN3 | |
| SCHEMBL9619639 | 0.80 | ATM (0.54) | ATMELANECTSKCTRB1PRTN3 | |
| SCHEMBL308291 | 0.80 | ATM (0.64) | ATMELANECTSKCTRB1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470672-B1 | COMPOUNDS FOR DETECTING PROTEASES | UNIV BELFAST (GB) | 2016-10-12 | — | — | EP | disclosed |
| US-9340820-B2 | Compounds and methods for protease detection | QUEEN'S UNIVERSITY OF BELFAST (GB) | 2016-05-17 | — | — | US | disclosed |
| US-20120156691-A1 | COMPOUND | QUEEN'S UNIVERSITY OF BELFAST | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120156691-A1 | COMPOUND | DNPEP, TMPRSS15, PEPD | ATM 4453/4885ELANE 51/4885CTSK 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.