Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 10/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938408 | 0.81 | HPGD (0.48) | HPGDSTSRECQLEPHX1PTPN2 | |
| SCHEMBL4612451 | 0.75 | HPGD (0.59) | HPGDSTSRECQLEPHX1PTPN2 | |
| SCHEMBL20428017 | 0.73 | HPGD (0.45) | HPGDSTSRECQLPTPN2PTPN1 | |
| SCHEMBL19397802 | 0.73 | HPGD (0.50) | HPGDSTSRECQLEPHX1PTPN2 | |
| SCHEMBL16291661 | 0.72 | HPGD (0.62) | HPGDSTSRECQLEPHX1PTPN2 | |
| SCHEMBL22719731 | 0.72 | HPGD (0.62) | HPGDSTSRECQLEPHX1PTPN2 | |
| SCHEMBL57231 | 0.72 | HPGD (0.62) | HPGDSTSRECQLEPHX1PTPN2 | |
| SCHEMBL17150677 | 0.72 | HPGD (0.62) | HPGDSTSRECQLEPHX1PTPN2 | |
| SCHEMBL43357 | 0.71 | HPGD (0.66) | HPGDSTSRECQLEPHX1PTPN2 | |
| SCHEMBL4405218 | 0.71 | RECQL (0.58) | HPGDSTSRECQLEPHX1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082947-A1 | COMPOUNDS AND COMPOSITIONS AS TGR5 AGONISTS | IRM LLC (BM) | 2012-06-21 | — | — | WO | disclosed |