Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK2 | P52789 | 9/20 | 0.48 |
| ▸ | HK1 | P19367 | 8/20 | 0.48 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761822 | 0.66 | PTGES2 (0.49) | SLC6A9CCR1ITGAVPTGES2 | |
| SCHEMBL1767644 | 0.65 | PTGES2 (0.54) | ITGAVPTGES2SLC40A1 | |
| SCHEMBL3872479 | 0.65 | PTGES2 (0.48) | SLC6A9PTGES2SLC40A1 | |
| SCHEMBL12916500 | 0.65 | FABP4 (0.51) | CCR1ITGAVPTGES2 | |
| SCHEMBL4029106 | 0.64 | PTGES2 (0.47) | SLC6A9PTGES2SLC40A1 | |
| SCHEMBL4031272 | 0.63 | ALDH1A1 (0.66) | PTGES2SLC40A1 | |
| SCHEMBL4962339 | 0.63 | CA12 (0.55) | SLC6A9PTGES2SLC40A1 | |
| SCHEMBL3866425 | 0.63 | CYP3A4 (0.49) | SLC6A9CCR1PTGES2SLC40A1 | |
| SCHEMBL9577190 | 0.62 | CYP3A4 (0.72) | CCR1 | |
| SCHEMBL14676306 | 0.62 | TSHR (0.42) | SLC6A9ITGAVPTGES2SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |