Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973054 | 0.91 | MAPT (0.41) | ALDH1A1MAPTSMN1; SMN2IDO1CYP2C9 | |
| SCHEMBL9973022 | 0.88 | MAPT (0.41) | ALDH1A1MAPTSMN1; SMN2IDO1CYP2C9 | |
| SCHEMBL9973041 | 0.88 | MAPT (0.41) | ALDH1A1MAPTSMN1; SMN2IDO1CYP2C9 | |
| SCHEMBL9973034 | 0.88 | MAPT (0.41) | ALDH1A1MAPTSMN1; SMN2IDO1CYP2C9 | |
| SCHEMBL11404438 | 0.81 | CYP2C9 (0.60) | ALDH1A1MAPTSMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL11412941 | 0.81 | CYP2C9 (0.46) | ALDH1A1MAPTSMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL9973040 | 0.80 | SLC6A2 (0.43) | ALDH1A1MAPTSMN1; SMN2IDO1CYP2C9 | |
| SCHEMBL11403234 | 0.80 | CYP2C9 (0.41) | ALDH1A1MAPTSMN1; SMN2IDO1CYP2C9 | |
| SCHEMBL11410614 | 0.79 | CYP2C9 (0.51) | ALDH1A1MAPTSMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL9973050 | 0.79 | ESR2 (0.46) | ALDH1A1MAPTSMN1; SMN2CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082383-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |