Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973064 | 0.91 | ALDH1A1 (0.41) | MAPTALDH1A1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL9973041 | 0.88 | MAPT (0.41) | MAPTALDH1A1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL9973034 | 0.88 | MAPT (0.41) | MAPTALDH1A1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL9973022 | 0.88 | MAPT (0.41) | MAPTALDH1A1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL11408378 | 0.81 | CYP2C9 (0.60) | MAPTALDH1A1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL11412500 | 0.81 | CYP2C9 (0.60) | MAPTALDH1A1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL11410805 | 0.81 | PRSS1 (0.46) | MAPTALDH1A1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL11405566 | 0.81 | PRSS1 (0.46) | MAPTALDH1A1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL9973040 | 0.80 | SLC6A2 (0.43) | MAPTALDH1A1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL11409703 | 0.80 | PRSS1 (0.41) | MAPTALDH1A1PRSS1ACRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082383-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20110279883-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2011-11-17 | — | — | US | disclosed |