Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 3/20 | 0.39 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973034 | 1.00 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1IDO1MGLL | |
| SCHEMBL9973022 | 1.00 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1IDO1MGLL | |
| SCHEMBL9973040 | 0.93 | SLC6A2 (0.43) | MAPTSMN1; SMN2ALDH1A1IDO1SLC6A2 | |
| SCHEMBL9973064 | 0.88 | ALDH1A1 (0.41) | MAPTSMN1; SMN2ALDH1A1IDO1ACR | |
| SCHEMBL9973054 | 0.88 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1IDO1ACR | |
| SCHEMBL9973051 | 0.83 | KMT2A (0.38) | SMN1; SMN2IDO1GRIA1GRIA2GRIA3 | |
| SCHEMBL9973052 | 0.82 | ELANE (0.40) | MAPTSMN1; SMN2ALDH1A1MGLLSLC6A2 | |
| SCHEMBL18078978 | 0.81 | ACR (0.46) | MAPTSMN1; SMN2ALDH1A1ACRHGFAC | |
| SCHEMBL12125148 | 0.80 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1MGLLACR | |
| SCHEMBL12125150 | 0.80 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1MGLLACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082383-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20110279883-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110143141-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143141-A1 | Photochromic compounds and compositions | CCNA1, CRY1, CCNT1 | MAPT 785/4885SMN1; SMN2 3964/4885ALDH1A1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.