SCHEMBL9973584

SCHEMBL9973584

C[C@]12CC[C@](C)(c3cc(O)c(O)cc31)c1cc(O)c(O)cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
RECQL P46063 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 2/20 0.36
ALOX12 P18054 2/20 0.36
KDM4E B2RXH2 1/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36
BLM P54132 1/20 0.36
CASP7 P55210 1/20 0.36
HSD17B10 Q99714 1/20 0.36
RXRA P19793 2/20 0.34
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
RARB P10826 1/20 0.33
TRPA1 O75762 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9988792 1.00 ALDH1A1 (0.36) ALDH1A1MAPTRECQLTDP1CYP3A4
SCHEMBL13105173 1.00 ALDH1A1 (0.36) ALDH1A1MAPTRECQLTDP1CYP3A4
SCHEMBL30131979 1.00 ALDH1A1 (0.36) ALDH1A1MAPTRECQLTDP1CYP3A4
SCHEMBL13925070 1.00 ALDH1A1 (0.36) ALDH1A1MAPTRECQLTDP1CYP3A4
SCHEMBL16674158 0.89 ALDH1A1 (0.39) ALDH1A1MAPTRECQLTDP1CYP3A4
SCHEMBL14413586 0.89 ALDH1A1 (0.39) ALDH1A1MAPTRECQLTDP1CYP3A4
SCHEMBL21730082 0.83 ALDH1A1 (0.36) ALDH1A1MAPTRECQLTDP1CYP3A4
SCHEMBL15347776 0.78 RXRA (0.50) CYP3A4RXRATP53CYP1A2RARB
SCHEMBL21440629 0.72 PTK2 (0.44) ALDH1A1TDP1CYP3A4THRBTP53
SCHEMBL19101607 0.72 CYP1A2 (0.42) ALDH1A1MAPTRECQLTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9522364-B2 Treated mixed matrix polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-20 US disclosed
US-9522364-B2 Treated mixed matrix polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-20 US disclosed
US-9492785-B2 UV and thermally treated polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-15 US disclosed
US-9492785-B2 UV and thermally treated polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-15 US disclosed
US-20160263532-A1 ULTRAVIOLET AND PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263532-A1 ULTRAVIOLET AND PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263533-A1 TREATED MIXED MATRIX POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263531-A1 PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263531-A1 PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263533-A1 TREATED MIXED MATRIX POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20120157743-A1 MEMBRANE SYSTEM FOR NATURAL GAS UPGRADING UOP LLC (US) 2012-06-21 US disclosed
US-20120157743-A1 MEMBRANE SYSTEM FOR NATURAL GAS UPGRADING UOP LLC (US) 2012-06-21 US disclosed
WO-2012082537-A2 MEMBRANE SYSTEM FOR NATURAL GAS UPGRADING UOP LLC (US) 2012-06-21 WO disclosed
US-7758751-B1 UV-cross-linked membranes from polymers of intrinsic microporosity for liquid separations UOP LLC (US) 2010-07-20 US disclosed
US-7485173-B1 Cross-linkable and cross-linked mixed matrix membranes and methods of making the same UOP LLC (US) 2009-02-03 US disclosed
US-20080295691-A1 UV CROSS-LINKED POLYMER FUNCTIONALIZED MOLECULAR SIEVE/POLYMER MIXED MATRIX MEMBRANES UOP LLC 2008-12-04 US disclosed
US-20080295692-A1 UV CROSS-LINKED POLYMER FUNCTIONALIZED MOLECULAR SIEVE/POLYMER MIXED MATRIX MEMBRANES FOR SULFUR REDUCTION UOP LLC 2008-12-04 US disclosed
US-20080300336-A1 UV CROSS-LINKED POLYMER FUNCTIONALIZED MOLECULAR SIEVE/POLYMER MIXED MATRIX MEMBRANES UOP LLC 2008-12-04 US disclosed
US-7410525-B1 Mixed matrix membranes incorporating microporous polymers as fillers UOP LLC (US) 2008-08-12 US disclosed
US-7410525-B1 Mixed matrix membranes incorporating microporous polymers as fillers UOP LLC (US) 2008-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157743-A1 MEMBRANE SYSTEM FOR NATURAL GAS UPGRADING PIM2, PIM1, PIM3 ALDH1A1 4736/4885MAPT 4534/4885RECQL 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.