Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934321 | 0.76 | ALDH1A1 (0.59) | PDE2AL3MBTL1RAB9ACYP3A4ALOX15 | |
| SCHEMBL5502229 | 0.75 | ALDH1A1 (0.44) | PDE2AL3MBTL1RAB9ACYP3A4LMNA | |
| SCHEMBL398001 | 0.75 | ALDH1A1 (0.44) | PDE2AL3MBTL1RAB9ACYP3A4LMNA | |
| SCHEMBL30397188 | 0.75 | ALDH1A1 (0.44) | PDE2AL3MBTL1RAB9ACYP3A4LMNA | |
| SCHEMBL31540276 | 0.73 | ALDH1A1 (0.41) | PDE2AL3MBTL1RAB9AUSP2ALOX15 | |
| SCHEMBL1275002 | 0.73 | ALDH1A1 (0.41) | PDE2AL3MBTL1RAB9AUSP2ALOX15 | |
| SCHEMBL30573716 | 0.73 | ALDH1A1 (0.63) | L3MBTL1RAB9ACYP3A4LMNAGAA | |
| SCHEMBL26607492 | 0.73 | ALDH1A1 (0.63) | L3MBTL1RAB9ACYP3A4LMNAGAA | |
| SCHEMBL526369 | 0.72 | HRH4 (0.40) | PDE2AL3MBTL1RAB9AUSP2ALOX15 | |
| SCHEMBL7082410 | 0.72 | MAPT (0.52) | L3MBTL1CYP3A4LMNAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203442-B1 | SUBSTITUTED PYRROLO-PYRIMIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2012-06-20 | — | — | EP | disclosed |