SCHEMBL30397188

SCHEMBL30397188

Nc1ccc(OC(F)(F)F)c(N)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.44
MAPT P10636 8/20 0.44
KDM4E B2RXH2 5/20 0.44
GAA P10253 4/20 0.44
CASP1 P29466 3/20 0.44
USP2 O75604 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
POLB P06746 2/20 0.44
ATM Q13315 2/20 0.44
TP53 P04637 1/20 0.44
HTT P42858 1/20 0.44
CASP7 P55210 1/20 0.44
L3MBTL1 Q9Y468 4/20 0.41
THRB P10828 2/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
G6PD P11413 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5502229 1.00 ALDH1A1 (0.44) ALDH1A1MAPTKDM4EGAACASP1
SCHEMBL398001 1.00 ALDH1A1 (0.44) ALDH1A1MAPTKDM4EGAACASP1
SCHEMBL9367414 0.84 GAA (0.40) ALDH1A1MAPTKDM4EGAACASP1
SCHEMBL30234869 0.83 TSHR (0.43) ALDH1A1KDM4EGAAUSP2POLB
SCHEMBL9224896 0.83 TSHR (0.43) ALDH1A1KDM4EGAAUSP2POLB
SCHEMBL6310104 0.83 GAA (0.39) ALDH1A1MAPTKDM4EGAACASP1
SCHEMBL31533760 0.83 GAA (0.39) ALDH1A1MAPTKDM4EGAACASP1
SCHEMBL10498338 0.82 MAPT (0.46) ALDH1A1MAPTKDM4EGAACASP1
SCHEMBL7779423 0.81 EPHX2 (0.50) GAAPOLBTSHRGLAPDE2A
SCHEMBL945792 0.81 GAA (0.57) ALDH1A1MAPTKDM4EGAACASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4616929-A1 POLYAMIDE COMPOSITE MEMBRANE AND PREPARATION METHOD THEREFOR Wanhua Chemical Group Co., Ltd. (CN) 2025-09-17 EP claimed
WO-2024174089-A1 POLYAMIDE COMPOSITE MEMBRANE AND PREPARATION METHOD THEREFOR 万华化学集团股份有限公司 2024-08-29 WO claimed
CN-118526988-A Polyamide composite membrane and preparation method thereof 万华化学集团股份有限公司 2024-08-23 CN claimed
EP-4616929-A1 POLYAMIDE COMPOSITE MEMBRANE AND PREPARATION METHOD THEREFOR Wanhua Chemical Group Co., Ltd. (CN) 2025-09-17 EP disclosed
WO-2025074873-A1 POLYAMIDIMIDE, RESIN COMPOSITION, MOLDED ARTICLE, AND FILM 株式会社カネカ 2025-04-10 WO disclosed
WO-2025063230-A1 POLYIMIDE, RESIN COMPOSITION, MOLDED OBJECT, AND FILM 株式会社カネカ 2025-03-27 WO disclosed
WO-2024174089-A1 POLYAMIDE COMPOSITE MEMBRANE AND PREPARATION METHOD THEREFOR 万华化学集团股份有限公司 2024-08-29 WO disclosed
CN-118526988-A Polyamide composite membrane and preparation method thereof 万华化学集团股份有限公司 2024-08-23 CN disclosed
CN-113249816-B Transparent fiber and preparation method thereof 上海邃铸科技有限公司 2023-05-05 CN disclosed